Myocardial plasticity: cardiac development, regeneration and disease
نویسندگان
چکیده
منابع مشابه
Cardiac myocyte cell cycle control in development, disease, and regeneration.
Cardiac myocytes rapidly proliferate during fetal life but exit the cell cycle soon after birth in mammals. Although the extent to which adult cardiac myocytes are capable of cell cycle reentry is controversial and species-specific differences may exist, it appears that for the vast majority of adult cardiac myocytes the predominant form of growth postnatally is an increase in cell size (hypert...
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The notion of the adult heart as terminally differentiated organ without self-renewal potential has been undermined by the existence of a subpopulation of replicating myocytes in normal and pathological states. The origin and significance of these cells has remained obscure for lack of a proper biological context. We report the existence of Lin(-) c-kit(POS) cells with the properties of cardiac...
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ژورنال
عنوان ژورنال: Current Opinion in Genetics & Development
سال: 2016
ISSN: 0959-437X
DOI: 10.1016/j.gde.2016.05.029